We're adults. When did that happen? And how do we make it stop?

Meredith Grey

Communication. It's the first thing we really learn in life. Funny thing is, once we grow up, learn our words and really start talking the harder it becomes to know what to say. Or how to ask for what we really need.

Meredith Grey

For a kiss to be really good, you want it to mean something. You want it to be with someone you can't get out of your head, so that when your lips finally touch you feel it everywhere. A kiss so hot and so deep you never want to come up for air. You can't cheat your first kiss. Trust me, you don't want to. Cause when you find that right person for a first kiss, it's everything.

Alex Karev

Meredith Grey: You know how when you were a little kid and you believed in fairy tales, that fantasy of what your life would be, white dress, prince charming who would carry you away to a castle on a hill. You would lie in bed at night and close your eyes and you had complete and utter faith. Santa Claus, the Tooth Fairy, Prince Charming, they were so close you could taste them, but eventually you grow up, one day you open your eyes and the fairy tale disappears. Most people turn to the things and people they can trust. But the thing is its hard to let go of that fairy tale entirely cause almost everyone has that smallest bit of hope, of faith, that one day they will open their eyes and it will come true

Meredith Grey: At the end of the day faith is a funny thing. It turns up when you don't really expect it. Its like one day you realize that the fairy tale may be slightly different than you dreamed. The castle, well, it may not be a castle. And its not so important happy ever after, just that its happy right now. See once in a while, once in a blue moon, people will surprise you , and once in a while people may even take your breath away.

Meredith Grey: Maybe we like the pain. Maybe we're wired that way. Because without it, I don't know; maybe we just wouldn't feel real. What's that saying? Why do I keep hitting myself with a hammer? Because it feels so good when I stop.

Meredith Grey: Intimacy is a four syllable word for, "Here's my heart and soul, please grind them into hamburger, and enjoy." It's both desired, and feared. Difficult to live with, and impossible to live without. Intimacy also comes attached to the three R's... relatives, romance, and roommates. There are some things you can't escape. And other things you just don't want to know.

Meredith Grey: I wish there were a rulebook for intimacy. Some kind of guide to tell you when you've crossed the line. It would be nice if you could see it coming, and I don't know how you fit it on a map. You take it where you can get it, and keep it as long as you can. And as for rules, maybe there are none. Maybe the rules of intimacy are something you have to define for yourself.

Meredith Grey: Okay, here it is, your choice... it's simple, her or me, and I'm sure she is really great. But Derek, I love you, in a really, really big pretend to like your taste in music, let you eat the last piece of cheesecake, hold a radio over my head outside your window, unfortunate way that makes me hate you, love you. So pick me, choose me, love me.

Dr. Meredith Grey: I've heard that it's possible to grow up - I've just never met anyone who's actually done it. Without parents to defy, we break the rules we make for ourselves. We throw tantrums when things don't go our way, we whisper secrets with our best friends in the dark, we look for comfort where we can find it, and we hope - against all logic, against all experience. Like children, we never give up hope...

Dr. Meredith Grey: Pain, you just have to ride it out, hope it goes away on its own, hope the wound that caused it heals. There are no solutions, no easy answers, you just breath deep and wait for it to subside. Most of the time pain can be managed but sometimes the pain gets you where you least expect it. Hits way below the belt and doesn't let up. Pain, you just have to fight through, because the truth is you can't outrun it and life always makes more.

Dr. Meredith Grey: Denial. It's not just a river in Egypt. It's a freakin' ocean.

Dr. Meredith Grey: I have an aunt who whenever she poured anything for you she would say "Say when". My aunt would say "Say when" and of course, we never did. We don't say when because there's something about the possibility, of more. More tequila, more love, more anything. More is better.

---

Dr. Meredith Grey: To be a good surgeon, you have to think like a surgeon. Emotions are messy. Tuck them neatly away and step into a clean, sterile room where the procedure is simple. Cut, suture, close. But sometimes you're faced to a cut that won't heal. A cut that rips its stitches wide open.

Dr. Meredith Grey: There's something to be said about a glass half full. About knowing when to say when. I think it's a floating line. A barometer of need and desire. It's entirely up to the individual. And depends on what's being poured. Sometimes all we want is a taste. Other times there's no such thing as enough, the glass is bottomless. And all we want, is more.

---

Dr. Meredith Grey: Maybe we're not supposed to be happy. Maybe gratitude has nothing to do with joy. Maybe being grateful means recognizing what you have for what it is. Appreciating small victories. Admiring the struggle it takes simply to be human. Maybe we're thankful for the familiar things we know. And maybe we're thankful for the things we'll never know. At the end of the day, the fact that we have the courage to still be standing is reason enough to celebrate.

Dr. Meredith Grey: No-one likes to lose control, but as a surgeon there's nothing worse. It's a sign of weakness, of not being up to the task. And still there are times when it just gets away from you. When the world stops spinning and you realize that your shiny little scalpel isn't gonna save you. No matter how hard you fight it, you fall. And it's scary as hell. Except there's an upside to freefalling. It's the chance you give your friends to catch you.

Dr. Meredith Grey: The key to surviving a surgical internship is denial. We deny that we're tired, we deny that we're scared, we deny how badly we want to succeed. And most importantly, we deny that we're in denial. We only see what we want to see and believe what we want to believe, and it works. We lie to ourselves so much that after a while the lies start to seem like the truth. We deny so much that we can't recognize the truth right in front of our faces.

Dr. Meredith Grey: At the end of the day, there are some things you just can't help but talk about. Some things we just don't want to hear, and some things we say because we can't be silent any longer. Some things are more than what you say, they're what you do. Some things you say cause there's no other choice. Some things you keep to yourself. And not too often, but every now and then, some things simply speak for themselves.

Dr. Meredith Grey: Four hundred years ago, another well-known English guy had an opinion about being alone. John Donne. He thought we were never alone. Of course, it was fancier when he said it. "No man is an island entire unto himself." Boil down that island talk, and he just meant that all anyone needs is someone to step in and let us know we're not alone. And who's to say that someone can't have four legs. Someone to play with or run around with, or just hang out.

Dr. Meredith Grey: When you were a kid, it was Halloween candy. You hid it from your parents and you ate it until you got sick. In college, it was the heavy combo of youth, tequila and well, you know. As a surgeon, you take as much of the good as you can get because it doesn't come around nearly as often as it should. 'Cause good things aren't always what they seem. Too much of anything, even love, is not always a good thing.

Dr. Meredith Grey: How do you know when how much is too much? Too much too soon. Too much information. Too much fun. Too much love. Too much to ask... And when is it all just too much to bear?

Denny Duquette: I've been lying in this bed for close to a year, and I've had a lot of time to look back on my life. And the things that I remember best - those are the things I wasn't supposed to do and I did them anyway. The thing is, life is too damn short to be following these rules.

---

Dr. Miranda Bailey: Look at this. Everybody wants a life without pain. And what does it get you? She needs to be on a poster somewhere to remind people, pain is there for a reason.

---

Dr. Meredith Grey: The fantasy is simple. Pleasure is good. And twice as much pleasure is better. That pain is bad. And no pain is better. But the reality is different. The reality is that pain is there to tell us something. And there is only so much pleasure we can take without getting a stomachache. And maybe that's okay. Maybe some fantasies are only supposed to live in our dreams.

---

Dr. Meredith Grey: At the end of the day, when it comes down to it, all we really want is to be close to somebody. So this thing, where we all keep our distance and pretend not to care about each other, is usually a load of bull. So we pick and choose who we want to remain close to, and once we've chosen those people, we tend to stick close by. No matter how much we hurt them, the people that are still with you at the end of the day - those are the ones worth keeping. And sure, sometimes close can be too close. But sometimes, that invasion of personal space, it can be exactly what you need.

Dr. Derek Shepherd: So, who's next, Alex? He likes to sleep around... you two have that in common.
Dr. Meredith Grey: You don't get to call me a whore! When I met you, I thought I had met the person I would spend then rest of my life with. I was done. So all the boys, and all the bars, and all the obvious daddy issues... who cared? Because I was done. You left me! You chose Addison! I'm all glued back together now. I make no apologies for how I chose to repair what you broke. You don't get to call me a whore!

---

Dr. Isobel "Izzie" Stevens: I'm a pretty girl.
Dr. Richard Webber: What?
Dr. Isobel "Izzie" Stevens: I'm not being arrogant, it's just... it's just kinda a fact. For a long time I made a career for my looks, so I get it. I'm a pretty girl. And not from a certain angle way, in an obvious way. It's the blonde thing, and the big boobs thing. Big boobs are key to obvious pretty, if you know what I'm saying.
Dr. Richard Webber: Dr. Stevens...
Dr. Isobel "Izzie" Stevens: That's how men see me. I'm not a smart girl or an interesting girl. I'm a pretty girl. The blonde and the boobs confuses guys into thinking that I'm someone else. And I'm used to it. I'm used to them walking away when they realize... but then Denny goes and asks me to marry him.
Dr. Richard Webber: Is that why you cut the wires?
Dr. Isobel "Izzie" Stevens: He doesn't make me feel like I'm a pretty girl. He makes me feel like... like me. I think he might know me. And so if I did cut the L-Vad wire, and I'm not saying I did, but if I did then no. I don't feel guilty. And I know that I should and I would if it were anybody else. But I can't feel anything but happy.

Dr. Derek Shepherd: It's not the chase.
Dr. Meredith Grey: What?
Dr. Derek Shepherd: You and me. It is not the thrill of the chase. It's not a game. It's... it's your tiny ineffectual fists. And your hair.
Dr. Meredith Grey: My hair?
Dr. Derek Shepherd: It smells good. And you're very, very ballsy. It keeps me in line.
Dr. Meredith Grey: I'm still not going out with you.
Dr. Derek Shepherd: You say that now...

Meredith Grey
The thing people forget is how good it can feel when you finally set secrets free. Whether good or bad, at least they're out in the open. And once your secrets are out in the open, you don't have to hide behind them anymore. The problem with secrets is even when you think you're in control, you're not.

Derek Shepherd
[to Meredith who is drinking tequila and dancing in her front lawn] So you blew me off for a bottle of tequila? Tequila's no good for you. It doesn't call, doesn't write, not nearly as much fun to wake up to.